Cell & Gene Therapy · Cell-based Immunotherapy · HLA Typed Cells · Protein & Vaccine Production · Mammalian Protein Expression · Vaccine Manufacturing.

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CD47 (IAP, MER6, OA3) protein expression summary. This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occu rs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction.

-0.37. BCL3. 0.17. -0.30. LOC730091. Together, these findings identified a macrophage MIAT/miR-149-5p /CD47 pathway as a key factor in the development of Gene Knockdown Techniques.

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NCBI Description of CD47 This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. cell lines with CD47 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with CD47 gene/protein from the curated CTD Gene-Chemical Interactions dataset. Cd47 Gene Detail Summary Symbol. Cd47 Name. CD47 antigen (Rh-related antigen, integrin-associated signal transducer) Synonyms.

19 Apr 2019 CD47,or Integrin-associated protein (IAP), is first discovered in a study aimed at studying integrin αvβ3.

Gene Ontology (GO) annotations related to this gene include thrombospondin receptor activity. 2021-04-04 CD47 - CD47 molecule (human) This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal CD47 CD47 molecule Gene ID: 961, updated on 7-Mar-2021 Gene type: protein coding Also known as: IAP; OA3; MER6.

The gene CD47 may have Genomic and Proteomic products available from Sigma-Aldrich.

Cd47 gene

2021-01-14 · DQ893920 - Synthetic construct Homo sapiens clone IMAGE:100008380; FLH165697.01L; RZPDo839F08159D CD47 molecule (CD47) gene, encodes complete protein. AB590342 - Synthetic construct DNA, clone: pFN21AE1472, Homo sapiens CD47 gene for CD47 molecule, without stop codon, in Flexi system. The gene view histogram is a graphical view of mutations across CD47. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.

Cd47 gene

Diseases associated with CD47 include Hereditary Spherocytosis and Neonatal Meningitis. Among its related pathways are Integrin Pathway and Cell surface interactions at the vascular wall. Gene Ontology (GO) annotations related to this gene include thrombospondin receptor activity. 2021-04-04 · leukocyte surface antigen CD47, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 glycoprotein, Rh-related antigen, antigen identified by monoclonal antibody 1D8, antigenic surface determinant protein OA3, integrin associated protein, integrin-associated signal transducer.
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By FISH, Lindberg et al. (1994) mapped the CD47 gene to chromosome 3q13.1-q13.2. Animal Model Lindberg et al. (1996) made observations in gene-targeted mice indicating that integrin-associated protein plays a key role in host defense by participating both in polymorphonuclear migration in response to bacterial infection and in polymorphonuclear activation at extravascular sites.

GenBank Accession AK164165, Cd47, 3.20, 10.66, 0.049. NM_016957, Hmgn2, 3.20  CD47 is the latest immuno-oncology target and multiple companies are 076 - Krystal Biotech's NOVEL Gene Therapy for Rare Diseases | Interview with WX  Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet Defining the role of CD47 and SIRPα in murine B cell homeostasis. RNA/DNA extraction, reporter gene assays and gene expression profiling.


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Transcriptional control of the CD47 gene is incompletely understood and has only been studied in the context of neuronal development, where transcription of CD47 and concomitant neurite outgrowth relies on the transcription factor α-Pal/NRF-1 (Chang and Huang, 2004; Chang et al., 2005).

COL8A1. 0.47. -0.40. CD47. 0.21. -0.29. THAP2.